Category of nutritional additives. Functional group: compounds of trace elements| 3b301 | — | Cobalt(II) acetate tetrahydrate | - Additive compositionCobalt(II) acetate tetrahydrate, as crystals/granules, with a minimum content of 23 % cobaltParticles < 50 μm: below 1 %
- Characterisation of the active substanceChemical formula: Co(CH3COO)2 × 4H2OCAS number: 6147-53-1
- Analytical methods
- For the identification of acetate in the additive:
- European Pharmacopoeia monograph 01/2008:20301.
- For the crystallographic characterisation of additive:
- X-Ray diffraction.
- For the determination of total cobalt in the additive, premixtures, compound feed and feed materials:
- EN 15510 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES)or
- CEN/TS 15621 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES) after pressure digestion.
- For determination of particle size distribution:
- ISO 13320:2009 — Particle size analysis — Laser diffraction methods.
| ruminants with a functional rumen, equidae, lagomorphs, rodents, herbivore reptiles and zoo mammals | — | — | 1 (total) | 1.The additive shall be incorporated into compound feed in the form of a premixture.2.Protective measures shall be taken according to national regulations implementing EU legislation on health and safety at work including Council Directives 89/391/EEC, 89/656/EEC, 92/85/EEC and 98/24/EC. Appropriate protective gloves, respiratory and eye protection according to Council Directive 89/686/EEC shall be worn during handling.3.Declarations to be made on the labelling of the additive and premixture:- Cobalt content
- "It is recommended to limit the supplementation with Cobalt to 0,3 mg/kg in complete feed. In this context, the risk for Cobalt deficiency due to local conditions and the specific composition of the diet should be taken into account."
4.Declarations to be made on the instructions of use of the compound feed:"Protective measures to avoid exposure with Cobalt by inhalation or by dermal route should be taken." | 15 July 2023 |
| 3b302 | — | Cobalt(II) carbonate | - Additive compositionCobalt(II) carbonate, as powder, with a minimum content of 46 % cobaltCobalt carbonate: minimum 75 %Cobalt hydroxide: 3 % - 15 %Water: maximum 6 %Particles < 11 μm: below 90 %
- Characterisation of the active substancesChemical formula: CoCO3CAS number: 513-79-1
- Analytical methods
- For the identification of carbonate in the additive:
- European Pharmacopoeia monograph 01/2008:20301.
- For the crystallographic characterisation of additive:
- X-Ray diffraction.
- For the determination of total cobalt in the additive, premixtures, compound feed and feed materials:
- EN 15510 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES)or
- CEN/TS 15621 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES) after pressure digestion.
- For determination of particle size distribution:
- ISO 13320:2009 — Particle size analysis — Laser diffraction methods.
| ruminants with a functional rumen, equidae, lagomorphs, rodents, herbivore reptiles and zoo mammals | — | — | 1 (total) | 1.The additive shall be incorporated into compound feed in the form of a premixture. This compound feed shall be placed on the market in a non-powder form.2.Appropriate measures shall be taken to avoid the cobalt emission in the air and prevent the exposure by inhalation or by dermal route. If such measures are technically not feasible or not sufficient, protective measures shall be taken according to national regulations implementing EU legislation on health and safety at work including Directives 89/391/EEC, 89/656/EEC, 92/85/EEC, 98/24/EC and 2004/37/EC of the European Parliament and of the Council. Appropriate protective gloves, respiratory and eye protection according to Directive 89/686/EEC shall be worn during handling.3.Declarations to be made on the labelling of the additive and premixture:- Cobalt content
- "It is recommended to limit the supplementation with Cobalt to 0,3 mg/kg in complete feed. In this context, the risk for Cobalt deficiency due to local conditions and the specific composition of the diet should be taken into account."
4.Declarations to be made on the instructions of use of the compound feed:"Protective measures to avoid exposure with Cobalt by inhalation or by dermal route should be taken." | 15 July 2023 |
| 3b303 | — | Cobalt(II) carbonate hydroxide (2:3) monohydrate | - Additive compositionCobalt (II) carbonate hydroxide (2:3) monohydrate, as powder, with a minimum content of 50 % cobaltParticles < 50 μm: below 98 %
- Characterisation of the active substanceChemical formula: 2CoCO3 × 3Co(OH)2 × H2OCAS number: 51839-24-8
- Analytical methods
- For the identification of carbonate in the additive:
- European Pharmacopoeia monograph 01/2008:20301.
- For the crystallographic characterisation of additive:
- X-Ray diffraction.
- For the determination of total cobalt in the additive, premixtures, compound feed and feed materials:
- EN 15510 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES)or
- CEN/TS 15621 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES) after pressure digestion.
- For determination of particle size distribution:
- ISO 13320:2009 — Particle size analysis — Laser diffraction methods.
| ruminants with a functional rumen, equidae, lagomorphs, rodents, herbivore reptiles and zoo mammals | — | — | 1 (total) | 1.The additive shall be incorporated into compound feed in the form of a premixture. This compound feed shall be placed on the market in a non-powder form.2.Appropriate measures shall be taken to avoid the cobalt emission in the air and prevent the exposure by inhalation or by dermal route. If such measures are technically not feasible or not sufficient, protective measures shall be taken according to national regulations implementing EU legislation on health and safety at work including Directives 89/391/EEC, 89/656/EEC, 92/85/EEC, 98/24/EC and 2004/37/EC. Appropriate protective gloves, respiratory and eye protection according to Directive 89/686/EEC shall be worn during handling.3.Declarations to be made on the labelling of the additive and premixture:- Cobalt content
- "It is recommended to limit the supplementation with Cobalt to 0,3 mg/kg in complete feed. In this context, the risk for Cobalt deficiency due to local conditions and the specific composition of the diet should be taken into account."
4.Declarations to be made on the instructions of use of the compound feed:"Protective measures to avoid exposure with Cobalt by inhalation or by dermal route should be taken." | 15 July 2023 |
| 3b304 | — | Coated granulated cobalt(II) carbonate | - Additive compositionCoated granulated preparation of cobalt(II) carbonate with a cobalt content of 1 % - 5 %Coating agents (2,3 % - 3,0 %) and dispersants (choice of poly-oxy-ethylene, sorbitan monolaurate, glycerol polyethyleneglycol ricinoleate, polyethyleneglycol 300, sorbitol, and maltodextrin)Particles < 50 μm: below 1 %
- Characterisation of the active substanceChemical formula: CoCO3CAS number: 513-79-1
- Analytical methods
- For the identification of carbonate in the additive:
- European Pharmacopoeia monograph 01/2008:20301.
- For the crystallographic characterisation of additive:
- X-Ray diffraction.
- For the determination of total cobalt in the additive, premixtures, compound feed and feed materials:
- EN 15510 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES)or
- CEN/TS 15621 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES) after pressure digestion.
- For determination of particle size distribution:
- ISO 13320:2009 — Particle size analysis — Laser diffraction methods.
| ruminants with a functional rumen, equidae, lagomorphs, rodents, herbivore reptiles and zoo mammals | — | — | 1 (total) | 1.The additive shall be incorporated into feed in the form of a premixture.2.Protective measures shall be taken according to national regulations implementing EU legislation on health and safety at work including Directives 89/391/EEC, 89/656/EEC, 92/85/EEC and 98/24/EC. Appropriate protective gloves, respiratory and eye protection according to Directive 89/686/EEC shall be worn during handling.3.Declarations to be made on the labelling of the additive and premixture, if applicable:- Cobalt content
- "It is recommended to limit the supplementation with Cobalt to 0,3 mg/kg in complete feed. In this context, the risk for Cobalt deficiency due to local conditions and the specific composition of the diet should be taken into account."
| 15 July 2023 |
| 3b305 | — | Cobalt(II) sulphate heptahydrate | - Additive compositionCobalt(II) sulphate heptahydrate, as powder, with a minimum content of 20 % cobaltParticles < 50 μm: below 95 %
- Characterisation of the active substanceChemical formula: CoSO4 × 7H2OCAS number: 10026-24-1
- Analytical methods
- For the identification of sulphate in the additive:
- European Pharmacopoeia monograph 01/2008:20301.
- For the crystallographic characterisation of additive:
- X-Ray diffraction.
- For the determination of total cobalt in the additive, premixtures, compound feed and feed materials:
- EN 15510 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES)or
- CEN/TS 15621 — inductively coupled plasma optical (atomic) emission spectrometry (ICP-AES) after pressure digestion.
- For determination of particle size distribution:
- ISO 13320:2009 — Particle size analysis — Laser diffraction methods.
| ruminants with a functional rumen, equidae, lagomorphs, rodents, herbivore reptiles and zoo mammals | — | — | 1 (total) | 1.The additive shall be incorporated into compound feed in the form of a premixture. This compound feed shall be placed on the market in a non-powder form.2.Appropriate measures shall be taken to avoid the cobalt emission in the air and prevent the exposure by inhalation or by dermal route. If such measures are technically not feasible or not sufficient, protective measures shall be taken according to national regulations implementing EU legislation on health and safety at work including Directives 89/391/EEC, 89/656/EEC, 92/85/EEC, 98/24/EC and 2004/37/EC. Appropriate protective gloves, respiratory and eye protection according to Directive 89/686/EEC shall be worn during handling.3.Declarations to be made on the labelling of the additive and premixture:- Cobalt content
- "It is recommended to limit the supplementation with Cobalt to 0,3 mg/kg in complete feed. In this context, the risk for Cobalt deficiency due to local conditions and the specific composition of the diet should be taken into account."
4.Declarations to be made on the instructions of use of the compound feed:"Protective measures to avoid exposure with Cobalt by inhalation or by dermal route should be taken." | 15 July 2023 |