Commission Regulation (EC) No 2701/94 of 7 November 1994 amending Annexes I, II, III and IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin (Text with EEA relevance)
Commission Regulation (EC) No 2701/94of 7 November 1994amending Annexes I, II, III and IV to Council Regulation (EEC) No 2377/90 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin(Text with EEA relevance) THE COMMISSION OF THE EUROPEAN COMMUNITIES,Having regard to the Treaty establishing the European Community,Having regard to Council Regulation (EEC) No 2377/90 of 26 June 1990 laying down a Community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal originOJ No L 224, 18. 8. 1990, p. 1., as last amended by Commission Regulation (EC) No 1430/94OJ No L 156, 23. 6. 1994, p. 6., and in particular Articles 6, 7 and 8 thereof,Whereas, since the adoption of the Regulation, the Annexes have been amended a number of times; whereas, by reason of their number, their complexity and their dispersal among various Official Journals of the European Communities, the texts are difficult to use and thus lack the clarity which should be an essential feature of all legislation; whereas, they should therefore be consolidated; whereas on the same occasion the name or chemical description of some compounds should be rectified or made more precise and certain material errors should be corrected;Whereas the measures provided for in this Regulation are in accordance with the opinion of the Committee for the adaptation to technical progress of directives on the removal of technical barriers to trade in the veterinary medicinal products sector,HAS ADOPTED THIS REGULATION:
Article 1Annexes I, II, III and IV to Regulation (EEC) No 2377/90 are hereby amended as set out in the Annex hereto.
Article 2This Regulation shall enter into force on the 60th day following its publication in the Official Journal of the European Communities.
This Regulation shall be binding in its entirety and directly applicable in all Member States.Done at Brussels, 7 November 1994.For the CommissionMartin BangemannMember of the CommissionANNEX IIList of substances not subject to maximum residue limits1.Inorganic chemicals
Pharmacologically active substance(s)Animal speciesOther provisions
1.1.Hydrogen peroxideFish
1.2.SulphurBovine
Porcine
Ovine
Caprine
Equidae
1.3.Iodine and iodine inorganic compounds including:Sodium and potassium — iodideSodium and potassium — iodateIodophors including polyvinylpyrrolidone — iodineAll food producing species
1.4.Sodium chloriteBovineFor tropical use only
2.Organic compounds
Pharmacologically active substance(s)Animal speciesOthers provisions
2.1.Etiproston tromethamineBovine
Porcine
2.2.Ketanserin tartrateEquidae
2.3.Fertirelin acetateBovine
2.4.Human menopausal urinary gonadotrophinBovine
2.5.Lactic acidAll food producing species
2.6.MelatoninOvine
Caprine
2.7.Iodine organic compoundsIodoformAll food producing species
2.8.Acetyl cysteineAll food producing species
ANNEX""ANNEX IIIList of pharmacologically active substances used in veterinary medicinal products for which provisional maximum residue limits have been fixed1.Anti-infectious agents1.1.Chemotherapeutics1.1.1.Sulfonamides
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
All substances belonging to the sulfonamide groupParent drugBovine, ovine, caprine100 μg/kgMilkProvisional MRL expires on 1. 1. 1996. The combined total residues of all substances within the sulfonamide group should not exceed 100 μg/kg
1.1.2.Diamino pyrimidine derivates
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.1.2.1.TrimethoprimTrimethoprimAll food producing species50 μg/kgMuscle, liver, kidney, fat, milkProvisional MRL expires on 1. 1. 1996
1.1.3.Nitrofurans
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.1.3.1.FurazolidoneAll residues with intact 5-nitro structureAll food producing species5 μg/kgMuscle, liver, kidney, fatProvisional MRL expires on 1. 7. 1995
1.1.4.Nitroimidazoles
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.1.4.1.DimetridazoleAll residues with intact nitroimidazole structureAll food producing species10 μg/kgMuscle, liver, kidney, fatProvisional MRL expires on 1. 1. 1995
1.2.Antibiotics1.2.1.Tetracyclines
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
All substances belonging to the tetracycline groupParent drugAll food producing species600 μg/kgKidneyProvisional MRLs expire on 1. 1. 1996. The combined total residues of all substances within the tetracycline group should not exceed the limits indicated
300 μg/kgLiver
200 μg/kgEggs
100 μg/kgMuscle
100 μg/kgMilk
1.2.2.Macrolides
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.2.1.SpiramycinSpiramycinBovine, porcine300 μg/kgLiver,Provisional MRLs expire on 1. 7. 1995. The MRLs for liver, kidney and muscle apply to both the bovine and porcine species
200 μg/kgKidney,
50 μg/kgMuscle
Bovine150 μg/kgMilk
1.2.2.2.TylosinBovine100 μg/kgMuscle, liver, kidneyProvisional MRLs expire on 1. 7. 1995
Porcine
Poultry
Bovine50 μg/kgMilk
1.2.3.Thiamphenicol and related compounds
Pharmacologically active substance(s)Market residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.3.1.ThiamphenicolThiamphenicolBovinePoultry40 μg/kgMuscle, liver, kidney, fatProvisional MRL expires on 1. 1. 1996
2.Antiparasitic agents2.1.Agents acting against endo-parasites2.1.1.Benzimidazoles and pro-benzimidazoles
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
2.1.1.1.FebantelCombined residues of oxfendazole, oxfendazole sulfone and fenbendazoleAll food producing species1000 μg/kgLiverProvisional MRLs expire on 1. 7. 1995. The MRLs cover all residues of febantel, fenbendazole and oxfendazole
10 μg/kgMuscle, kidney, fat
10 μg/kgMilk
2.1.1.2.FenbendazoleCombined residues of oxfendazole, oxfendazole sulfone and fenbendazoleAll food producing species1000 μg/kgLiverProvisional MRLs expire on 1. 7. 1995. The MRLs cover all residues of febantel, fenbendazole and oxfendazole
10 μg/kgMuscle, kidney, fat
10 μg/kgMilk
2.1.1.3.OxfendazoleCombined residues of oxfendazole, oxfendazole sulfone and fenbendazoleAll food producing species1000 μg/kgLiverProvisional MRLs expire on 1. 7. 1995. The MRLs cover all residues of febantel, fenbendazole and oxfendazole
10 μg/kgMuscle, kidney, fat
10 μg/kgMilk
2.1.1.4.AlbendazoleSum of albendazole and metabolites which are measured as 2-amino-benzimidazole sulphoneBovine100 μg/kgMuscle, fat, milk,Provisional MRLs expire on 1. 1. 1996
Ovine500 μg/kgKidney
1000 μg/kgLiver
2.1.1.5.ThiabendazoleSum of thiabendazole and 5-hydroxythiabendazoleBovine100 μg/kgMuscle, liver, kidney, fat, milkProvisional MRLs expire on 1. 1. 1996
Ovine
Caprine
2.1.1.6.TriclabendazoleSum of extractable residues that may be oxidized to ketotriclabendazoleBovine150 μg/kgMuscle, liver, kidneyProvisional MRLs expire on 1. 7. 1995
Ovine50 μg/kgFat
2.1.1.7.FlubendazoleFlubendazolePoultry500 μg/kgLiver,Provisional MRLs expire on 1. 1. 1996
Game birds200 μg/kgMuscle,
400 μg/kgEggs
Porcine10 μg/kgMuscle, liver, kidney, fat
2.1.1.8.OxibendazoleOxibendazoleBovineOvine100 μg/kgMuscle, liver, kidney, fatProvisional MRLs expire on 1. 1. 1996
50 μg/kgMilk
PorcineEquidae100 μg/kgMuscle, liver, kidney, fat
2.1.2.Tetra-hydro-imidazoles (imidazolthiazoles)
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
2.1.2.1.LevamisoleLevamisoleAll food producing species10 μg/kgMusle, liver, kidney, fat, milkProvisional MRL expires on 1. 1. 1995
2.2.Agents acting against ectoparasites
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
2.2.1.AmitrazSum of amitraz and metabolites which are measured as 2,4-dimethylanilinePorcine50 μg/kgMuscleProvisional MRLs expire on 1. 7. 1996.
200 μg/kgKidney, liver
3.Agents acting on the nervous system3.1.Agents acting on the central nervous system3.1.1.Butyrophenone tranquilizers
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
3.1.1.1.AzaperoneAzaperolAll food producing species100 μg/kgKidneyProvisional MRLs expire on 1. 1. 1996
50 μg/kg1Liver, muscle, fat
3.2.Agents acting on the autonomic nervous system3.2.1.Anti-adrenergics
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
3.2.1.1.CarazololCarazololAll food producing species30 μg/kgLiverProvisional MRLs expire on 1. 7. 1995
5 μg/kgKidney, muscle, fat
ANNEX IList of pharmacologically active substances for which maximum residue limits have been fixed1.Anti-infectious agents1.1.Chemotherapeutics1.1.1.Sulfonamides
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
All substances belonging to the sulfonamide groupParent drugAll food producing species100 μg/kgMuscle, liver, kidney, fatThe combined total residues of all substances within the sulfonamide group should not exceed 100 μg/kg
1.2.Antibiotics1.2.1.Penicillins
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.1.1.BenzylpenicillinBenzylpenicillinAll food producing species50 μg/kgMuscle, liver, kidney, fat
4 μg/kgMilk
1.2.1.2.AmpicillinAmpicillinAll food producing species50 μg/kgMuscle, liver, kidney, fat
4 μg/kgMilk
1.2.1.3.AmoxicillinAmoxicillinAll food producing species50 μg/kgMuscle, liver, kidney, fat
4 μg/kgMilk
1.2.1.4.OxacillinOxacillinAll food producing species300 μg/kgMuscle, liver, kidney, fat
30 μg/kgMilk
1.2.1.5.CloxacillinCloxacillinAll food producing species300 μg/kgMuscle, liver, kidney, fat
30 μg/kgMilk
1.2.1.6.DicloxacillinDicloxacillinAll food producing species300 μg/kgMuscle, liver, kidney, fat
30 μg/kgMilk
1.2.2.Cephalosporins
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.2.1.CefquinomeCefquinomeBovine200 μg/kgKidney
100 μg/kgLiver
50 μg/kgMuscle
50 μg/kgFat
1.2.3.Quinolones
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.3.1.EnrofloxacinSum of enrofloxacin and ciprofloxacinBovine, porcine, poultry30 μg/kgMuscle, liver, kidney
1.2.4.Macrolides
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
1.2.4.1. TilmicosinTilmicosinBovine1000 μg/kgLiver, kidney
50 μg/kgMuscle, fat
2.Antiparasitic agents2.1.Agents acting against endoparasites2.1.1.Avermectins
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
2.1.1.1.Ivermectin22,23- Dihydroavermectin B1aBovine100 μg/kgLiver
40 μg/kgFat
Porcine15 μg/kgLiver
Ovine20 μg/kgFat
Equidae
2.1.1.2.AbamectinAvermectin B1aBovine20 μg/kgLiver
10 μg/kgFat
2.1.1.3.DoramectinDoramectinBovine15 μg/kgLiver
25 μg/kgFat
2.1.2Salicylanilides
Pharmacologically active substance(s)Marker residueAnimal speciesMRLsTarget tissuesOther provisions
2.1.2.1.ClosantelClosantelBovine1000 μg/kgMuscle, liver
3000 μg/kgKidney, fat
Ovine1500 μg/kgMuscle, liver
5000 μg/kgKidney, fat
2000 μg/kg
ANNEX IVList of pharmacologically active substances for which no maximum levels can be fixed1.Nitrofurans, except furazolidone (see Annex III)2.Ronidazole3.Dapsone4.Chloramphenicol